ViPC Research & Innovation Platform in Pigmentary Medicine | Clinical Trials, Technology Validation & Translational Research

ViPC Vitiligo & Pigment Research Center

Advancing Innovation and Translation in Pigmentary Medicine

ViPC is a clinical and translational research platform dedicated to vitiligo and pigmentary disorders. We integrate clinical trials, medical devices and therapeutic technologies, advanced skin imaging, artificial intelligence, translational research, and melanocyte regeneration to advance innovative research from scientific discovery to clinical application. 

Clinical Research | Technology Validation | Translational Collaboration
 

Research Platform

An Integrated Platform Dedicated to Pigmentary Research

ViPC combines specialized clinical expertise in pigmentary disorders with comprehensive research capabilities, supporting drug development, therapeutic technology studies, skin imaging validation, and mechanistic research. 
 

Phase I–IV Clinical Trials

Support for study feasibility assessment, participant recruitment, standardized study visits, safety monitoring, study documentation, and clinical trial implementation.

Specialized Assessment of Pigmentary Disorders

Standardized assessments including VASI and MASI, disease activity and stability evaluation, repigmentation assessment, Wood’s lamp examination, and standardized photography.

Advanced Skin Imaging

OCT, dermoscopy, Wood’s lamp imaging, standardized digital photography, and quantitative image analysis.

Translational Research Platform

Clinical biospecimens, immune profiling, primary human melanocytes, melanogenesis assays, and three-dimensional pigmented skin models.

Therapeutic Technology Research

Research involving lasers, microneedling, radiofrequency microneedling, combination therapies, and cell-based therapies.

Our Research Capabilities

Six Core Research Areas

Our research focuses on pigmentary disorders and integrates clinical development, technology validation, and mechanistic investigation.
 

01 | Clinical Trials & Emerging Therapies

Phase I–IV clinical trials, industry-sponsored studies, and investigator-initiated research covering systemic therapies, targeted treatments, topical therapies, and pigmentary disorders in both adults and children.

02 | Medical Devices, Lasers & Therapeutic Technologies

Research on lasers, microneedling, radiofrequency microneedling, energy-based medical devices, combination therapies, and technologies for pigment restoration.

03 | Skin Imaging, Technology Validation & Artificial Intelligence

OCT, RCM, Wood’s lamp imaging, dermoscopy, standardized photography, quantitative image analysis, medical technology validation, and AI applications.

04 | Melasma & Aesthetic Dermatology Research

Clinical evaluation of pigment-modulating products, aesthetic dermatology products, topical treatments, medical devices, and combination therapies for melasma and hyperpigmentation disorders.

05 | Translational Immunology & Pigment Biology

Longitudinal immune profiling, biomarker research, primary human melanocytes, inflammatory models, melanogenesis, and three-dimensional pigmented skin models.

06 | Melanocyte Regeneration & Cell Therapy

Research into melanocyte protection, microenvironmental biology, cell transplantation, transplantation optimization, and regenerative strategies aimed at achieving more durable pigment restoration.
 

Clinical Development × Innovative Technologies

From Clinical Trial Execution to Objective Treatment Assessment

Clinical Trials → Therapeutic Technologies & Medical Devices → Advanced Phenotyping → Clinical Evidence

Clinical Trials & Emerging Therapies

ViPC has participated in multiple Phase I–IV clinical studies in vitiligo and other pigmentary disorders, including industry-sponsored and investigator-initiated studies involving novel systemic immunomodulatory therapies, targeted treatments, and topical therapies.

Our assessment capabilities include standardized vitiligo and melasma scoring systems such as VASI and MASI, quality-of-life measures, standardized polarized photography, Wood’s lamp examination, dermoscopy, quantitative skin image analysis, and long-term efficacy and safety follow-up.
 

Medical Devices, Lasers & Therapeutic Technologies

Our research includes fractional and pigment-targeting lasers, microneedling, radiofrequency microneedling, energy-based medical devices, device–drug combination therapies, and therapeutic strategies for both hypopigmentary and hyperpigmentary disorders.

Applications include vitiligo, melasma, depigmentation, treatment-associated pigmentary changes, pigment restoration, and technologies supporting cell-based therapies.
 

Skin Imaging, Technology Validation & Artificial Intelligence

We use non-invasive skin imaging and quantitative analysis to support diagnosis, assessment of disease activity and stability, treatment monitoring, and the development of more objective efficacy endpoints for clinical trials.

Our imaging platform includes Wood’s lamp examination, dermoscopy, spectrophotometric analysis, standardized digital photography, quantitative image analysis, non-invasive OCT tissue imaging, and AI/algorithm validation. 
 

Translational Research

From Clinical Phenotypes to Melanocyte Biology

At ViPC, we aim not only to determine whether a treatment works, but also to understand why it works and how pigment restoration can be made more durable. 
 

Translational Immunology & Pigment Biology

We integrate clinical phenotypes with blood-, tissue-, and skin imaging–based biomarkers to investigate inflammatory pathways, treatment response, disease recurrence, and mechanisms of melanocyte injury.

Our research platform includes:

• High-dimensional immune profiling

• Longitudinal biomarker studies

• Primary human melanocytes

• Melanocyte inflammatory models

• Melanogenesis and dendricity analysis

• Reconstructed pigmented epidermis and 3D skin models

Melanocyte Regeneration & Cell Therapy

Our regenerative research focuses on melanocyte survival, differentiation, melanogenesis, cell–cell adhesion, extracellular matrix and basement membrane microenvironments, cell transplantation, and post-transplant regenerative strategies.

Long-Term Research Direction

Our long-term goal is to move beyond preventing melanocyte destruction toward restoring functional melanocytes and establishing durable pigment regeneration.
 

Collaborate with ViPC

One Center. Multiple Models of Research Collaboration.

We welcome collaborations with pharmaceutical and biotechnology companies, medical device developers, skin imaging and AI teams, aesthetic dermatology and skincare companies, regenerative medicine companies, and academic research groups.
 

Pharmaceuticals / Biologics

Phase I–IV Clinical Trials + Biomarkers

Medical Devices / Lasers

Clinical Validation + Objective Efficacy Endpoints

Imaging / Artificial Intelligence

Technology Validation + Digital Biomarkers

Aesthetic Dermatology Products

Clinical Efficacy Studies in Melasma and Pigmentation

Regenerative Therapies

Melanocytes / 3D Models + Clinical Translation

Academic Research

Clinical Cohorts + Biospecimens + Mechanistic Research 
 

Have a New Therapy, Technology, or Research Question?

We welcome opportunities to discuss clinical trials, study feasibility, medical device and imaging technology validation, translational research, biomarkers, melanocyte biology, and regenerative medicine collaborations. 
 

ViPC Vitiligo & Pigment Research Center
Chang Gung Memorial Hospital | Taiwan