先進皮膚成像系統在診斷面部色素性和炎症性疾病中的比較研究

摘要:
視覺評估雖然是臨床實踐中評估色素沉著和紅斑的主要方法，但它具有主觀性、耗時性，且可能導致臨床醫師之間觀察結果的差異。為了準確評估疾病的嚴重程度和治療的有效性，需要客觀且量化的技術。本研究檢驗了一種新開發的皮膚成像系統在評估色素沉著和紅斑方面的精確度和實用性。研究招募了60名參與者，並使用新型OBSERV 520 x皮膚成像系統對其面部圖像進行分析，與DERMACATCH進行區域分析和VISIA進行全臉檢查進行比較。皮膚色素沉著的程度通過皮膚科醫生評估的MASI分數進行臨床分級。數據顯示，新型皮膚成像系統與兩種傳統儀器在量化色素沉著和紅斑方面存在正相關，無論是在區域分析還是全臉分析中。此外，新型皮膚成像系統與臨床MASI分數之間也存在正相關（r = 0.4314, P < 0.01）。相比之下，我們的研究發現傳統系統與臨床評估之間沒有顯著相關性，表明新系統在評估色素過度沉著方面具有更強的能力。我們的研究驗證了這種創新皮膚成像系統在評估色素沉著和紅斑方面的準確性，展示了其在臨床和研究目的中進行量化評估的可行性。

Visual assessment, while the primary method for pigmentation and erythema evaluation in clinical practice, is subjective, time-consuming, and may lead to variability in observations among clinicians. Objective and quantitative techniques are required for a precise evaluation of the disease's severity and the treatment's efficacy. This research examines the precision and utility of a newly developed skin imaging system in assessing pigmentation and erythema. Sixty participants were recruited, and their facial images were analyzed with the new OBSERV 520 x skin imaging system, compared to DERMACATCH for regional analysis and VISIA for full-face examination. The degree of skin pigmentation was clinically graded using the MASI scores evaluated by dermatologists. The data revealed positive correlations between the novel skin imaging system and the two conventional instruments in quantifying pigmentation and erythema, whether in regional or full-face analysis. Furthermore, the new skin imaging system positively correlated with the clinical MASI scores (r = 0.4314, P < 0.01). In contrast, our study found no significant correlation between the traditional system and clinical assessment, indicating a more substantial capacity for hyperpigmentation assessment in the new system. Our study validates the innovative skin imaging system's accuracy in evaluating pigmentation and erythema, demonstrating its feasibility for quantitative evaluation in both clinical and research purposes.